Rainforest Discovery may Erase Some Diseases and Signs of Aging

A tree that grows in the Amazon rainforest is offering new hope for diseases ranging from arthritis to irritable bowel syndrome. It also could stop signs of aging.
According to researchers at Case Western Reserve University/University Hospitals of Cleveland, a product derived from the Sangre de grado (Croton palanostigma) tree effectively keeps enzymes known as matrix metalloproteinases (MMPs) from snipping collagen out of tissue. Collagen forms the basis for cartilage and is responsible for holding the tissues together. MMPs are active during inflammation and thus play a role in numerous diseases.
The discovery has led to the development of an antioxidant called Progrado, which researchers believe may one day help treat arthritis and other inflammatory conditions. The treatment might even be effective against wrinkles and other signs of aging.
“This is the first time a natural product has been shown to directly block these molecular scissors while showing potential to stimulate repair,” study author Tariq Haqqi, PhD., writes. “This is a testament to the wound healing properties of this traditional medicine and the distinctive therapeutic opportunities that nature offers.”
“Of course, more research will be needed,” writes Dr. Haqqi and his fellow authors, to determine whether extracts like Progrado “provide meaningful therapeutic value in arthritis, joint injury and repair.”

SOURCE: Journal of Inflammation, Oct. 29, 2007