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Monday, 19 August 2013
Researchers at the University of Illinois have discovered that celery, along with artichokes, herbs, and especially Mexican oregano, all contain apigenin and luteolin, flavonoids that kill human pancreatic cancer cells by inhibiting an important enzyme.
The scientists found that apigenin inhibited an enzyme called glycogen synthase kinase-3ß (GSK-3ß), which led to a decrease in the production of anti-apoptotic genes in the pancreatic cancer cells. Apoptosis means that the cancer cell self-destructs because its DNA has been damaged.
Researchers realize that pancreatic cancer patients would probably not be able to eat enough flavonoid-rich foods to raise blood plasma levels of the flavonoid to an effective level. However, scientists are confident that they could design drugs that would achieve those concentrations.
SOURCE: University of Illinois College of Agricultural, Consumer and Environmental Sciences, August 2013