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Tuesday, 15 October 2013
Identical twins with significant weight differences shed light on the phenomenon of metabolically healthy obesity
A rare study from the Obesity Research Unit, University of Helsinki, Helsinki, Finland tested 16 sets of identical twins, obese and lean, to find if the leaner twin is more healthy than the obese twin.
Dr. Kirsi Pietiläinen, Dr. Jussi Naukkarinen, and other researchers found that 8 of the 16 sets of identical twins consisted of a metabolically healthy obese twin and a lean co-twin. The other half of the sets of twins consisted of one unhealthy obese twin who had high liver fat, increased insulin production and resistance, poor fat profile and high blood pressure.
The metabolically healthy obese twin did not have health issues; the obese twin was just as healthy as the lean twin. The twins ranged from ages 23 to 36 and had a BMI range between 20 to 40, but doctors say that the MHO stage will vary as the twin ages and accumulates excessive weight.
"Weight differences between the groups were similar, but a given weight difference may have different metabolic effects depending on where in the distribution of BMI a pair is located," researchers were quoted saying.
SOURCE: Diabetologia, October 2013